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Comparison of Physician-, Biomarker-r and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma.

Authors :
Calhoun, William J.
Ameredes, Bill T.
King, Tonya S.
Icitovic, Nikolina
Bleecker, Eugene R.
Castro, Mario
Cherniack, Reuben M.
Chinchilli, Vernon M.
Craig, Timothy
Denlinger, Loren
DiMango, Emily A.
Engle, Linda L.
Fahy, John V.
Grant, J. Andrew
Israel, Elliot
Jarjour, Nizar
Kazani, Shamsah D.
Kraft, Monica
Kunselman, Susan J.
Lazarus, Stephen C.
Source :
JAMA: Journal of the American Medical Association. 9/12/2012, Vol. 308 Issue 10, p987-997. 11p.
Publication Year :
2012

Abstract

The article presents a randomized clinical trial, Best Adjustment Strategy for Asthma in the Long Term (BASALT) to determine the adjustments of inhaled corticosteroid therapy in preventing treatment failure in adults with mild to moderate asthma. The study concluded that the adults with mild to moderate persistent asthma controlled with low-dose inhaled corticosteroid therapy. It is suggested to use symptom-based adjustment strategies because it is simple to use and empower patients.

Details

Language :
English
ISSN :
00987484
Volume :
308
Issue :
10
Database :
Academic Search Index
Journal :
JAMA: Journal of the American Medical Association
Publication Type :
Academic Journal
Accession number :
79813814
Full Text :
https://doi.org/10.1001/2012.jama.10893