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Microwave-Assisted and Iodine-Catalyzed Synthesis of Dihydropyrimidin-2-thiones via Biginelli Reaction Under Solvent-Free Conditions.

Authors :
Liu, Qingjian
Pan, Ning
Xu, Jiehua
Zhang, Wenwen
Kong, Fanpeng
Source :
Synthetic Communications. Jan2013, Vol. 43 Issue 1, p139-146. 8p. 3 Diagrams, 2 Charts.
Publication Year :
2013

Abstract

Microwave-assisted synthesis of 3,4-dihydropyrimidin-2-thiones via Biginelli reaction from aldehydes, acetoacetates, and thiourea in the presence of iodine under solvent-free conditions has been accomplished in good yields and purity without chromatographic separation. [ABSTRACT FROM PUBLISHER]

Details

Language :
English
ISSN :
00397911
Volume :
43
Issue :
1
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
79723009
Full Text :
https://doi.org/10.1080/00397911.2011.593289