Back to Search
Start Over
Ultrasound and radiology surrogate endpoints in pharmacological studies
- Source :
-
Atherosclerosis (00219150) . Sep2012, Vol. 224 Issue 1, p12-24. 13p. - Publication Year :
- 2012
-
Abstract
- Abstract: Cardiovascular studies investigating therapeutic intervention with clinical endpoints are costly due to the need for considerable duration and large number of patients, or both. Therefore, for evaluation of novel cardiovascular drug efficacy, surrogate endpoints are used. Cardiovascular imaging endpoints have proven their worth. Sometimes the relevance of imaging is questioned and other methods are suggested instead. There is also some confusion about the strengths of imaging endpoints. The aim of the present paper is to review ultrasound and radiology imaging techniques as surrogate endpoints in pharmacological trials. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00219150
- Volume :
- 224
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Atherosclerosis (00219150)
- Publication Type :
- Academic Journal
- Accession number :
- 79338723
- Full Text :
- https://doi.org/10.1016/j.atherosclerosis.2012.03.038