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Microbial/enzymatic synthesis of chiral intermediates for pharmaceuticals
- Source :
-
Enzyme & Microbial Technology . Nov2002, Vol. 31 Issue 6, p804. 23p. - Publication Year :
- 2002
-
Abstract
- There has been an increasing awareness of the enormous potential of microorganisms and enzymes for the transformation of synthetic chemicals with high chemo-, regio- and enatioselective manner. Chiral intermediates and fine chemicals are in high demand both from pharmaceutical and agrochemical industries for the preparation bulk drug substances and agricultural products. In this review article, microbial/enzymatic processes have been described for the synthesis of chiral intermediates for anticancer drugs, antiviral agents, β3-receptor agonists, antihypertensive drugs, melatonin receptor agonists, anticholesterol drugs, and anti-Alzheimer’s drugs. [Copyright &y& Elsevier]
- Subjects :
- *CHIRAL drugs
*ENZYMATIC analysis
Subjects
Details
- Language :
- English
- ISSN :
- 01410229
- Volume :
- 31
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Enzyme & Microbial Technology
- Publication Type :
- Academic Journal
- Accession number :
- 7892687
- Full Text :
- https://doi.org/10.1016/S0141-0229(02)00186-2