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Enhanced separation of filamentous fungi by ultrasonic field: possible usage in repeated batch processes
- Source :
-
Journal of Biotechnology . Aug2002, Vol. 97 Issue 2, p191. 7p. - Publication Year :
- 2002
-
Abstract
- Usage of ultrasonic field-based filters in retention of filamentous fungal cells was assessed using Rhizopus arrhizus NRRL 1526 as a model organism. Effects of operating conditions, such as power input, harvest pump flow rate, run time and stop time, on the system''s separation efficiency (SE) were evaluated by modulating the variables according to a Central Composite Design (CCD). The standard pump with which the ultrasonic filter was equipped was shown to be unsuitable and was, therefore, substituted for with a prime rate reverse pump that made possible separation and recycle of the mycelial biomass. The operating conditions were optimised (run time, 300 s; stop time, 3 s; power input, 6 W; harvest pump flow rate, 4 l per day) and a repeated batch process (three batches for a total of 192 h) was performed during which the SE was maintained always higher than 88%. [Copyright &y& Elsevier]
- Subjects :
- *FUNGI
*FILTERS & filtration
Subjects
Details
- Language :
- English
- ISSN :
- 01681656
- Volume :
- 97
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 7821758
- Full Text :
- https://doi.org/10.1016/S0168-1656(02)00062-7