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Maintained Serum Sodium in Male Ultra-Marathoners -- The Role of Fluid Intake, Vasopressin, and Aldosterone in Fluid and Electrolyte Regulation.
- Source :
-
Hormone & Metabolic Research . Aug2011, Vol. 43 Issue 9, p646-652. 7p. - Publication Year :
- 2011
-
Abstract
- Exercise-associated hyponatremia (EAH) is a well know electrolyte disorder in endurance athletes. Although fluid overload is the most like etiology, recent studies, however, argued whether EAH is a disorder of vasopressin secretion. The aims of the present study were to investigate (i) the prevalence of EAH in male ultra-marathoners and (ii) whether fluid intake, aldosterone or vasopressin, as measured by copeptin, were associated with post-race serum sodium concentration ([Na+]). In 50 male ultra-marathoners in a 100 km ultra-marathon, serum [Na+], aldosterone, copeptin, serum and urine osmolality, and body mass were measured pre- and post-race. Fluid intake, renal function parameters and urine excretion were measured. No athlete developed EAH. Copeptin and aldosterone increased; a significant correlation was found between the change in copeptin and the change in serum [Na+], no correlation was found between aldosterone and serum [Na+]. Serum [Na+] increased by 1.6 %; body mass decreased by 1.9 kg. The change in serum [Na+] and body mass correlated significantly and negatively. The fluid intake of ~0.58 l/h was positively related to the change in body mass and negatively to both post-race serum [Na+] and the change in serum [Na+]. We conclude that serum [Na+] was maintained by both the mechanisms of fluid intake and the hormonal regulation of vasopressin. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYPONATREMIA
*VASOPRESSIN
*ALDOSTERONE
*BODY fluids
*SERUM
*DISEASES in athletes
Subjects
Details
- Language :
- English
- ISSN :
- 00185043
- Volume :
- 43
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Hormone & Metabolic Research
- Publication Type :
- Academic Journal
- Accession number :
- 78079904
- Full Text :
- https://doi.org/10.1055/s-0031-1284352