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Tributylphosphine-catalyzed Stetter reaction of N,N-dimethylacrylamide: synthesis of N,N-dimethyl-3-aroylpropionamides

Authors :
Gong, Ji Hyeon
Im, Yang Jin
Lee, Ka Young
Kim, Jae Nyoung
Source :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Feb2002, Vol. 43 Issue 7, p1247. 5p.
Publication Year :
2002

Abstract

The reaction of arylaldehydes 1 and N,N-dimethylacrylamide in the presence of tributylphosphine afforded N,N-dimethyl-3-aroylpropionamides 2 in moderate yields. The reaction might involve the formation of α-oxo ylide A. [Copyright &y& Elsevier]

Subjects

Subjects :
*CATALYSIS
*ALDEHYDES
*ACRYLAMIDE

Details

Language :
English
ISSN :
00404039
Volume :
43
Issue :
7
Database :
Academic Search Index
Journal :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :
Academic Journal
Accession number :
7746550
Full Text :
https://doi.org/10.1016/S0040-4039(01)02344-9