Salutary effect of resveratrol on sepsis-induced myocardial depression.

The article discusses a study which tested whether resveratrol administration would reverse downregulation of peroxisome proliferator to activated receptor-, coactivator 1α, preserve mitochondrial integrity and prevent sepsis-induced myocardial failure in mice. It concluded that the effects of resveratrol on cecal ligation and puncture-induced myocardial dysfunction are associated with increased peroxisome proliterater-activated receptor-~, coactivator 1α abundance and function.