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Synthesis of 1-Substituted 4(1 H )-Quinazolinones Under Solvent-Free Conditions.

Authors :
Wang, Yao
Zhang, Mei
Cao, Shengli
Lin, Huihui
Gao, Man
Li, Zhongfeng
Source :
Synthetic Communications. Sep2012, Vol. 42 Issue 18, p2715-2727. 13p. 4 Diagrams, 2 Charts.
Publication Year :
2012

Abstract

Heating a mixture of 2-(N-alkylamino)benzoic acids, triethyl orthoformate, and ammonium acetate under solvent-free conditions generated 1-substituted 4(1H)-quinazolinones in 73−99% yields. Moreover, a possible reaction pathway was proposed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00397911
Volume :
42
Issue :
18
Database :
Academic Search Index
Journal :
Synthetic Communications
Publication Type :
Academic Journal
Accession number :
76170884
Full Text :
https://doi.org/10.1080/00397911.2011.566407