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Aphanalides A–H, ring A-seco limonoids from the fruits of Aphanamixis polystachya
- Source :
-
Tetrahedron . May2012, Vol. 68 Issue 21, p3963-3971. 9p. - Publication Year :
- 2012
-
Abstract
- Abstract: Eight new ring A-seco limonoids, aphanalides A–H (1–8) were isolated from the fruits of Aphanamixis polystachya. Aphanalides A–C (1–3) are the first examples of ring A-seco limonoids with an unusual oxetane ring between C-7 and C-14. The structures of aphanalide A (1) and aphanalide C (3) were confirmed by single-crystal X-ray studies. Their structures including absolute stereochemistry were established on the basis of extensive NMR spectroscopic analysis, by comparison of experimental and calculated electron circular dichroism (ECD) and by X-ray diffraction, representing the first report of assignment of absolute configuration of such type ring A-seco limonoids. The biogenetic origin of aphanalides A–D (1–4) from aphanalides E–H (5–8) was also postulated. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 68
- Issue :
- 21
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 74553825
- Full Text :
- https://doi.org/10.1016/j.tet.2012.03.083