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Adiposity, Its Related Biologic Risk Factors, and Suicide: A Cohort Study of 542,088 Taiwanese Adults.
- Source :
-
American Journal of Epidemiology . Apr2012, Vol. 175 Issue 8, p804-815. 12p. - Publication Year :
- 2012
-
Abstract
- Recent studies in Western nations have shown inverse associations between body mass index (BMI, measured as weight (kg)/height (m)2) and suicide. However, it is uncertain whether the association is similar in non-Western settings, and the biologic pathways underlying the association are unclear. The authors investigated these issues in a cohort of 542,088 Taiwanese people 20 years of age or older who participated in a health check-up program (1994–2008); there were 573 suicides over a mean 8.1 years of follow up. There was a J-shaped association between BMI and suicide risk (P for the quadratic term = 0.033) but limited evidence of a linear association (adjusted hazard ratio per 1-standard-deviation increase = 0.95 (95% confidence interval: 0.85, 1.06)); compared with individuals whose BMI was 18.5–22.9, adjusted hazard ratios for those with a BMI <18.5 or ≥35 were 1.56 (95% confidence interval: 1.07, 2.28) and 3.62 (95% confidence interval: 1.59, 8.22), respectively. A high waist-to-hip ratio was associated with an increased risk of suicide. There was some evidence for a reverse J-shaped association of systolic blood pressure and high density lipoprotein cholesterol with suicide and an association of higher triglyceride level with increased suicide risk; these associations did not appear to mediate the associations of BMI and waist-to-hip ratio with suicide. [ABSTRACT FROM PUBLISHER]
- Subjects :
- *SUICIDE risk factors
*ADIPOSE tissues
*ATTRIBUTION (Social psychology)
*BLOOD pressure
*CONFIDENCE intervals
*STATISTICAL correlation
*CAUSES of death
*HIGH density lipoproteins
*LONGITUDINAL method
*CULTURAL pluralism
*RESEARCH funding
*TRIGLYCERIDES
*SECONDARY analysis
*BODY mass index
*REPEATED measures design
*PROPORTIONAL hazards models
*WAIST-hip ratio
*DESCRIPTIVE statistics
Subjects
Details
- Language :
- English
- ISSN :
- 00029262
- Volume :
- 175
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- American Journal of Epidemiology
- Publication Type :
- Academic Journal
- Accession number :
- 74494627
- Full Text :
- https://doi.org/10.1093/aje/kwr386