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Transfusion-related alloimmune neutropenia: an undescribed complication of blood transfusion.
- Source :
-
Lancet . 10/5/2002, Vol. 360 Issue 9339, p1073. 2p. 1 Chart, 1 Graph. - Publication Year :
- 2002
-
Abstract
- Alloimmune neutropenia in neonates is rare. We describe severe and persistent neutropenia in a 4-week-old neonate, which arose within 2 h of a transfusion of blood that contained about 28 mL of plasma and in which strong antibodies against human neutrophil antigen 1b (HNA-1b) were subsequently identified. The infant was positive for HNA-1b. No other likely cause of neutropenia was discovered. We believe this complication of blood transfusion to be a previously unrecognised one, and have called the condition transfusion-related alloimmune neutropenia (TRAIN). [ABSTRACT FROM AUTHOR]
- Subjects :
- *NEUTROPENIA
*BLOOD transfusion reaction
*NEONATAL diseases
*CLINICAL medicine
Subjects
Details
- Language :
- English
- ISSN :
- 01406736
- Volume :
- 360
- Issue :
- 9339
- Database :
- Academic Search Index
- Journal :
- Lancet
- Publication Type :
- Academic Journal
- Accession number :
- 7447623
- Full Text :
- https://doi.org/10.1016/S0140-6736(02)11132-9