Sedentary Behavior Is Not Associated with Cardiometabolic Risk in Adults with Abdominal Obesity.

Objective: The primary aim of this study was to determine whether time spent in sedentary behaviors (SED) was associated with 2-hour glucose and insulin resistance in adults with abdominal obesity. We also examined the association between light physical activity (LPA) and sporadic (accumulated in bouts ,10 minutes in duration) moderate-to-vigorous physical activity (MVPA) with glucose metabolism. Methods: Participants were 135 inactive, abdominally obese adults recruited from Kingston, Canada. SED and physical activity were determined by accelerometry over 7 days and summarized as SED (accelerometer counts/min ,100), LPA (counts/min 100-1951), and MVPA (counts/min ⩾1952). A 75 g oral glucose tolerance test was used to ascertain 2-hour glucose; the homeostasis model of assessment was used to determine insulin resistance (HOMA-IR); lipid, lipoproteins and blood pressure were determined using standard protocols. Secondary analyses considered the association between SED and physical activity with other cardiometabolic risk factors Results: Participants spent 627.2682.9 min/d in SED, 289.0691.7 min/d in LPA and 19.2±13.5 min/d in MVPA. Neither SED nor the physical activity variables were associated with 2-hour glucose or HOMA-IR (p.0.05). In secondary analyses, SED was not associated with any cardiometabolic risk factor (p.0.1); with the exception of blood pressure (p,0.05), LPA was not associated with any cardiometabolic risk factor (p.0.1); and MVPA was independently associated with total cholesterol and triglycerides (p,0.05). Conclusions: Objectively measured SED was not associated with 2-hr glucose or HOMA-IR. Our findings also suggest that the accumulation of LPA and sporadic MVPA is not associated with glucose metabolism in adults with abdominal obesity [ABSTRACT FROM AUTHOR]