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Intraoperative gamma probe detection of insulinoma in an elderly patient with pancreatic cystic lesions.
- Source :
-
Clinical Endocrinology . Oct2002, Vol. 57 Issue 4, p547-549. 3p. - Publication Year :
- 2002
-
Abstract
- Summary Insulinoma is a rare endocrine tumour in the elderly. We report the case of an 81-year-old woman suffering from grand mal seizures. Insulinoma was suspected because plasma glucose and insulin levels were 1·5 mmol/l and 80·4 pmol/l, respectively. A pancreatic computerized tomography (CT) scan, magnetic resonance imaging (MRI) and arteriography were normal but 111 In-DTPA-octreotide scintigraphy detected a hotspot in the pancreatic tail. Intraoperative pancreatic ultrasonography and palpation were non-contributory due to multiple pancreatic cysts and nodular lesions. However, a gamma-detecting probe localized a small tumour, labelled preoperatively with 111 In-DTPA-octreotide. Intraoperative insulin measurements in portal venous blood confirmed the successful removal of an insulinoma that was 6 mm in diameter histologically. Pancreatic cystic lesions increase with age and make the intraoperative localization of the insulinoma difficult. Intraoperative gamma probe detection of the tumour labelled with 111 In-DTPA-octreotide might therefore constitute a useful surgical tool. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ISLANDS of Langerhans tumors
*ENDOCRINE gland tumors
*PANCREATIC cysts
Subjects
Details
- Language :
- English
- ISSN :
- 03000664
- Volume :
- 57
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Clinical Endocrinology
- Publication Type :
- Academic Journal
- Accession number :
- 7406196
- Full Text :
- https://doi.org/10.1046/j.1365-2265.2002.01646.x