A Lewis acid-promoted reduction of acylsilanes to α-hydroxysilanes by diethylzinc

Authors :: Gao, Guang
Bai, Xing-Feng
Li, Fei
Zheng, Long-Sheng
Zheng, Zhan-Jiang
Lai, Guo-Qiao
Jiang, Kezhi
Li, Fuwei
Xu, Li-Wen
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Apr2012, Vol. 53 Issue 17, p2164-2166. 3p.
Publication Year :: 2012
Abstract: Abstract: We report here the first example of the reduction of acylsilanes to α-hydroxysilanes, in which diethylzinc was used as a highly reactive agent in the presence of Ti(OiPr)4 or other Lewis acids. The reduction typically proceeds to give synthetically useful α-hydroxysilanes in good yields. [Copyright &y& Elsevier]

Subjects :: *LEWIS acids
*CHEMICAL reduction
*ACYLSILANES
*DIETHYLZINC
*REACTIVITY (Chemistry)
*TITANIUM compounds
*ORGANIC synthesis

Language :: English
ISSN :: 00404039
Volume :: 53
Issue :: 17
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 73892362
Full Text :: https://doi.org/10.1016/j.tetlet.2012.02.059

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