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Identification and optimization of small molecule antagonists of vasoactive intestinal peptide receptor-1 (VIPR1)

Authors :
Harikrishnan, Lalgudi S.
Srivastava, Neelam
Kayser, Lauren E.
Nirschl, David S.
K, Kumaragurubaran
Roy, Amrita
Gupta, Anuradha
Karmakar, Sukhen
Karatt, Tajudheen
Mathur, Arvind
Burford, Neil T.
Chen, Jing
Kong, Yan
Cvijic, MaryEllen
Cooper, Christopher B.
Poss, Michael A.
Trainor, George L.
Wong, Tai W.
Source :
Bioorganic & Medicinal Chemistry Letters. Mar2012, Vol. 22 Issue 6, p2287-2290. 4p.
Publication Year :
2012

Abstract

Abstract: Identification, synthesis and structure–activity relationship of small-molecule VIPR1 antagonists encompassing two chemical series are described. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0960894X
Volume :
22
Issue :
6
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
73364055
Full Text :
https://doi.org/10.1016/j.bmcl.2012.01.082