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Rapidly involuting congenital haemangioma (RICH) of the liver.
- Source :
-
Pediatric Radiology . Mar2012, Vol. 42 Issue 3, p308-314. 7p. - Publication Year :
- 2012
-
Abstract
- Background: Rapidly involuting congenital haemangioma (RICH) is a benign neoplasm that may occur in many locations in the body. When RICH occurs in the liver, it may be confused with other lesions. Objective: To present a case series from a single institution. Materials and methods: Retrospective review of pathological and imaging findings in infants with biopsy-proven hepatic RICH treated at a single hospital. Results: Four children (2 days to 6 weeks of age) presented between 2002 and 2007 with a solitary hepatic lesion. Needle biopsy excluded the alternative possibility of infantile haemangioma by showing negativity for GLUT1. Serial imaging confirmed rapid involution in each child. Conclusion: RICH should be suspected in neonates who present with a solitary liver lesion and normal-for-age serum alpha-fetoprotein. Serial US scans should be used to confirm a progressive shrinkage of the lesion. Corticosteroids and β-adrenergic antagonists have no proven effect in treating RICH. If the lesion grows, percutaneous needle biopsy is recommended to exclude a malignant tumour and to direct further management. Infants with cardiac failure should be treated medically. Embolization (with or without needle biopsy) should only be performed when this strategy fails. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 03010449
- Volume :
- 42
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Pediatric Radiology
- Publication Type :
- Academic Journal
- Accession number :
- 73277908
- Full Text :
- https://doi.org/10.1007/s00247-011-2268-z