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E-Cadherin/β-Catenin Complex and the Epithelial Barrier.
- Source :
-
Journal of Biomedicine & Biotechnology . 2011, p1-6. 6p. - Publication Year :
- 2011
-
Abstract
- E-Cadherin/β-catenin complex plays an important role in maintaining epithelial integrity and disrupting this complex affect not only the adhesive repertoire of a cell, but also the Wnt-signaling pathway. Aberrant expression of the complex is associated with a wide variety of human malignancies and disorders of fibrosis resulting from epithelial-mesenchymal transition. These associations provide insights into the complexity that is likely responsible for the fibrosis/tumor suppressive action of E-cadherin/β-catenin. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 11107243
- Database :
- Academic Search Index
- Journal :
- Journal of Biomedicine & Biotechnology
- Publication Type :
- Academic Journal
- Accession number :
- 71520454
- Full Text :
- https://doi.org/10.1155/2011/567305