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Medullary thyroid cancer and pseudocirrhosis: case report and literature review.
- Source :
-
Current Oncology . Feb2012, Vol. 19 Issue 1, pe36-e41. 6p. 2 Color Photographs, 2 Charts, 1 Graph. - Publication Year :
- 2012
-
Abstract
- Pseudocirrhosis is a rare form of liver disease that can cause clinical symptoms and radiographic signs of cirrhosis; however, its histologic features suggest a distinct pathologic process. In the setting of cancer, hepatic metastases and systemic chemotherapy are suspected causes of pseudocirrhosis. Here, we present a patient with medullary thyroid carcinoma metastatic to the liver who developed pseudocirrhosis while on maintenance sunitinib after receiving 5-fluorouracil, leucovorin, and oxaliplatin (FOLFOX) in combination with sunitinib. Cirrhotic change in liver morphology was accompanied by diffusely infiltrative carcinomatous disease resembling the primary tumor. We discuss the diagnosis of pseudocirrhosis in this case and review the literature regarding pseudocirrhosis in cancer. [ABSTRACT FROM AUTHOR]
- Subjects :
- *LIVER diseases
*LIVER metastasis
*DRUG therapy
Subjects
Details
- Language :
- English
- ISSN :
- 11980052
- Volume :
- 19
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Current Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 71496403
- Full Text :
- https://doi.org/10.3747/co.19.840