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Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case.
- Source :
-
Surgery Today . Feb2012, Vol. 42 Issue 2, p181-184. 4p. - Publication Year :
- 2012
-
Abstract
- Dilated cardiomyopathy (DCM) is a heart muscle disease characterized by progressive heart failure, and is a leading cause of mortality and morbidity. Recently, cellular therapy for end-stage heart failure has been emerging. We herein report a 56-year-old male who received a transplant of autologous myoblast sheets manufactured in temperature-responsive culture dishes. His clinical condition improved markedly, leaving him without any arrhythmia and able to discontinue using a left ventricular assist system and avoid cardiac transplantation. These findings suggest that cellular therapy using myoblast sheets is a promising new strategy for treating patients with end-stage DCM. This method might be an effective alternative to heart transplantation in the near future. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09411291
- Volume :
- 42
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Surgery Today
- Publication Type :
- Academic Journal
- Accession number :
- 70532113
- Full Text :
- https://doi.org/10.1007/s00595-011-0106-4