The Effect of Weight Loss and Exercise Training on Flow-Mediated Dilatation in Coronary Heart Disease.

The article presents a randomized trial on the effect of exercise training and weight reduction on flow-mediated dilatation (FMD) in overweight patients with coronary heart disease (CHD). The study reveals that patients randomized to the higher-caloric exercise condition lost more weight and experienced a greater percentage increase in branchial artery FMD than in the lower-caloric-expenditure exercise group. It concludes that exercise and weight loss increased FMD in such patients with CHD.