BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.

Investigates the association of male germ-line-specific protein with epigenetic reprogramming events. Involvement of the 11-zinc-finger factor in gene regulation; Formation of methylation-sensitive insulators; Identification of the methylation marks in somatic cells.