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Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.

Authors :
Schreiber-Agus, Nicole
Meng, Yong
Hoang, Tin
Hou, Jr., Harry
Chen, Ken
Greenberg, Roger
Cordon-Cardo, Carlos
Lee, Han-Woong
DePinho, Ronald A.
Source :
Nature. 6/4/1998, Vol. 393 Issue 6684, p483. 5p. 16 Color Photographs, 3 Black and White Photographs, 2 Diagrams, 6 Graphs.
Publication Year :
1998

Abstract

Presents research which showed that mice lacking the Mxi1 protein exhibit progressive, multisystem abnormalities. Mxi1 an antagonist of Myc oncoproteins; Possibility that Mxi1 is a tumor-suppressor gene; Chromosomal location of gene; Traits of mice; Proliferative ability of Mxi1-deficient cell types; Role of Mxi1.

Details

Language :
English
ISSN :
00280836
Volume :
393
Issue :
6684
Database :
Academic Search Index
Journal :
Nature
Publication Type :
Academic Journal
Accession number :
700663
Full Text :
https://doi.org/10.1038/31008