Polyamine depletion prevents camptothecin-induced apoptosis by inhibiting the release of cytochrome c.

Authors :: Qing Yuan
Ray, Ramesh M.
Johnson, Leonard R.
Source :: American Journal of Physiology: Cell Physiology. Jun2002, Vol. 282 Issue 6, pC1290. 8p. 6 Diagrams, 4 Graphs.
Publication Year :: 2002
Abstract: Examines the influence of polyamine depletion in preventing capotothecin-induced apoptosis. Inhibition of the release of cythocrome; Regulation of apoptosis in mammalian cells; Role of the mitochondria.

Subjects :: *POLYAMINES
*APOPTOSIS
*CYTOCHROMES
*MITOCHONDRIA
*REACTIVITY (Chemistry)

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