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Análise da ação da Himatanthus drasticus na progressão do câncer de pulmão induzido por uretana em camundongos.
- Source :
-
Einstein (16794508) . Jul2011, Vol. 9 Issue 3, p350-353. 4p. 1 Color Photograph, 2 Graphs. - Publication Year :
- 2011
-
Abstract
- Objective: To evaluate the effect of janaguba in inhibiting the development of lung cancer in an experimental urethane-induced model. Methods: a total of 3 mg/kg urethane was injected in 51 Balb-C mice aged 7-13 weeks of life. Janaguba was administered orally daily in two doses: 0.04 mL (Group 2, G2) and 0.06 mL (Group 3, G3), for 20 weeks. After this period, the mice were sacrificed and the number of lesions counted. Results: The mean weight of Group 2 was lower than that of Group 3, and that of Group 1 (Control, G1) (G1 = 35.533 g; G2 = 33.359 g; G3 = 37.125 g). The number of nodules did not differ between groups (mean G1 = G2 = G3 = 1; p = 0.88). Conclusion: Janaguba had an effect on the growth of mice, but had no influence on the progression of lung cancer in this model. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Portuguese
- ISSN :
- 16794508
- Volume :
- 9
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Einstein (16794508)
- Publication Type :
- Academic Journal
- Accession number :
- 69700983