UV Resonance Raman Study of Β93-Modified Hemoglobin A: Chemical Modifier-Specific Effects...

Authors :: Juszczak, Laura J.
Manjula, Belur
Bonaventura, Celia
Acharya, Seetharama A.
Friedman, Joel M.
Source :: Biochemistry. 1/8/2002, Vol. 41 Issue 1, p376. 10p. 1 Diagram, 1 Chart, 8 Graphs.
Publication Year :: 2002
Abstract: Evaluates the conformational consequences of chemically modifying the Cys beta93 sulfhydryl group of both the deoxy and carbon monoxide-saturated derivatives of human adult hemoglobin. Effect of the conformation of both linker chemistry and poly(ethylene glycol) size; Generation of several derivatives through a maleimide reaction with sulfhydryl.

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