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Trypanocidal Activity of Oxoaporphine and Pyrimidine-β-Carboline Alkaloids from the Branches of Annona foetida Mart. (Annonaceae).
- Source :
-
Molecules . Nov2011, Vol. 16 Issue 11, p9714-9720. 7p. 1 Diagram, 1 Chart. - Publication Year :
- 2011
-
Abstract
- Phytochemical investigation of the branches of Annona foetida Mart. led to isolation from the CH2Cl2 extract of four alkaloids: Atherospermidine (1), described for the first time in this species, liriodenine (2), O-methylmoschatoline (3), and annomontine (4). Their chemical structures were established on the basis of spectroscopic data from IR, MS, NMR (1D and 2D), and comparison with the literature. Compounds 2-4 showed potent trypanocidal effect when evaluated against epimastigote and trypomastigote forms of Trypanosoma cruzi. [ABSTRACT FROM AUTHOR]
- Subjects :
- *PYRIMIDINES
*CARBOLINES
*ALKALOIDS
*ANNONA
*TRYPANOSOMA cruzi
Subjects
Details
- Language :
- English
- ISSN :
- 14203049
- Volume :
- 16
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Molecules
- Publication Type :
- Academic Journal
- Accession number :
- 67734920
- Full Text :
- https://doi.org/10.3390/molecules16119714