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A randomized, controlled pilot trial of hormone therapy for menopausal insomnia.
- Source :
-
Archives of Women's Mental Health . Dec2011, Vol. 14 Issue 6, p505-508. 4p. - Publication Year :
- 2011
-
Abstract
- Insomnia is a frequent climacteric symptom. This pilot, double-blind, randomized placebo-controlled trial compared estradiol associated with trimegestone or placebo in 12 women with perimenopausal insomnia. The Pittsburgh Sleep Quality Index (PSQI) was administered, and polysomnography was performed at baseline and after 28 days. Sleep efficiency and median score of the PSQI improved significantly in the hormone therapy group (HT) ( p = 0.041 and p = 0.027, respectively) and not in placebo group. Perimenopausal insomnia improved after short-term HT. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ESTRADIOL
*THERAPEUTIC use of progestational hormones
*ANALYSIS of variance
*CHI-squared test
*FISHER exact test
*HORMONE therapy
*INSOMNIA
*MENOPAUSE
*STATISTICS
*T-test (Statistics)
*U-statistics
*POLYSOMNOGRAPHY
*PILOT projects
*DATA analysis
*BODY mass index
*RANDOMIZED controlled trials
*BLIND experiment
*DATA analysis software
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 14341816
- Volume :
- 14
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Archives of Women's Mental Health
- Publication Type :
- Academic Journal
- Accession number :
- 67693866
- Full Text :
- https://doi.org/10.1007/s00737-011-0242-2