Construction of central composite designs for balanced orthogonal blocks.

Box & Hunter (1957) recommended a set of orthogonally blocked central composite designs (CCD) when the region of interest is spherical. In order to achieve rotatability along with orthogonal blocking, the block size for those designs becomes unequal and it may not be attractive or practical to use such unequally blocked designs in many practical situations. In this paper, a construction method of orthogonally blocked CCD under the assumption of equal block size is proposed and an index of block orthogonality is introduced. [ABSTRACT FROM AUTHOR]