Synthesis, spectroscopic, thermal, and biological activities of mixed ligand complexes containing E-N′-(3,4,5-trimethoxybenzylidene)benzofuran-2-carbohydrazide and 2-aminothiophenol.

Complexes [M(L)(L′)Cl · H2O], where M = Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II), L = ligand derived from reaction between benzofuran-2-carbohydrazide and 3,4,5-trimethoxybenzaldehyde (TMeOBFC) and L′ = 2-aminothiophenol (2-atp), have been synthesized. The structures of the complexes have been proposed from analytical data, IR, UV-Vis, 1H NMR, direct analysis in real time-mass spectra, ESR spectral data, magnetic, and thermal studies. The complexes are soluble in DMF and DMSO. Molar conductance values indicate that the complexes are non-electrolytes. Antibacterial and antifungal activities of the ligands and their metal complexes have been obtained against bacteria Escherichia coli and Staphylococcus aureus and against fungi Aspergillus niger and Aspergillus flavus. [ABSTRACT FROM AUTHOR]