[Commentary on] Annual high-dose vitamin D supplementation does not affect mental well-being in older women.

The authors comment on a study by K. M. Sanders and colleagues which claims that annual oral high dose vitamin D supplements have no effect on the mental conditions of older women, although it increases serum 25-hydroxyvitamin D levels. According to the authors, Sanders and colleagues pointed out the limitations of their study as they should have, but no clear justification for the use of high dose vitamin D was given. They add that the study provides some useful information to clinicians.