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A 1:1 cocrystal of fluconazole with salicylic acid.

Authors :
Kastelic, Jože
Lah, Nina
Kikelj, Danijel
Leban, Ivan
Source :
Acta Crystallographica: Section C (Wiley-Blackwell). Sep2011, Vol. 67 Issue 9, po370-o372. 3p.
Publication Year :
2011

Abstract

The article discusses a research study on the interaction of pharmaceutical agent fluconazole with salicylic acid in a 1:1 ratio. Researchers dissolved equimolar amounts of salicylic acid and fluconazole in acetonitrile at 323 degrees Kelvin (K) and gained colourless crystals for analysis. Results showed that molecules of salicylic acid and fluconazole formed homomeric centrosymmetric dimers through hydrogen bonds.

Details

Language :
English
ISSN :
01082701
Volume :
67
Issue :
9
Database :
Academic Search Index
Journal :
Acta Crystallographica: Section C (Wiley-Blackwell)
Publication Type :
Academic Journal
Accession number :
66757212
Full Text :
https://doi.org/10.1107/S0108270111031155