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Total Synthesis of Landomycin A, a Potent Antitumor Angucycline Antibiotic.
- Source :
-
Journal of the American Chemical Society . 8/17/2011, Vol. 133 Issue 32, p12433-12435. 3p. - Publication Year :
- 2011
-
Abstract
- The first total synthesis of landomycin A, the longest and most potent antitumor angucycline antibiotic, has been achieved in 63 steps and 0.34% overall yield starting from 2,5-dihydroxybenzoic acid, 3,5-dimethylphenol, triacetyl d-glucal, and d-xylose, with a convergent linear sequence of 21 steps. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00027863
- Volume :
- 133
- Issue :
- 32
- Database :
- Academic Search Index
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 65264435
- Full Text :
- https://doi.org/10.1021/ja205339p