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Supravenous hyperpigmentation, transverse leuconychia and transverse melanonychia after chemotherapy for Hodgkin’s disease.
- Source :
-
Journal of the European Academy of Dermatology & Venereology . Mar2002, Vol. 16 Issue 2, p162-163. 2p. 2 Black and White Photographs. - Publication Year :
- 2002
-
Abstract
- Abstract Pigmentary abberations of the skin, mucosa and epidermal appendages are common side-effects after systemic treatment with chemotherapeutic agents. These pigment changes appear in different patterns and are partly quite typical for the applied chemotherapeutic drug. The pathogenesis of the different skin pigmentations are not well known. The most often discussed causes are the stimulation of melanocytes, involvement of the tyrosinase enzyme system and thrombophlebitis with postinflammatory hyperpigmentation by the aggressive substances. Nail discolorations are mainly due to direct toxic effects and stimulation of the matrix melanocytes. We report a rare event of supravenous hyperpigmentation, transverse leuconychia and melanonychia after chemotherapy of a patient suffering from Hodgkin’s disease. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HODGKIN'S disease treatment
*DRUG therapy
Subjects
Details
- Language :
- English
- ISSN :
- 09269959
- Volume :
- 16
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of the European Academy of Dermatology & Venereology
- Publication Type :
- Academic Journal
- Accession number :
- 6525222
- Full Text :
- https://doi.org/10.1046/j.1468-3083.2002.00424.x