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Occurrence of Hepatocellular Carcinoma Was Not a Rare Event during and Immediately after Antiviral Treatment in Japanese HCV-Positive Patients.
- Source :
-
Oncology . 2011, Vol. 80 Issue 5/6, p366-372. 7p. - Publication Year :
- 2011
-
Abstract
- Advanced chronic hepatitis C patients with sustained virolological response by antivirals remain at risk for hepatocellular carcinoma (HCC). We investigated the incidence of HCC during and immediately after peginterferon-alfa-2a and ribavirin (RBV) treatment in patients with chronic hepatitis C in Japan. HCC was detected in 8 of 238 patients during and after these treatments (mean follow-up period: 572 ± 252 days). In conclusion, occurrence of HCC is not a rare event during and immediately after peginterferon-alfa-2a plus RBV treatment. In cases with cirrhosis, higher α-fetoprotein levels, old age, or a previous history of HCC treatment, clinicians should be especially alert for the possible development of HCC during and immediately after peginterferon-alfa-2a and RBV treatment. Clinicians should regularly check for the possible development of HCC even in chronic hepatitis C patients under treatment. Copyright © 2011 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
- Subjects :
- *HEPATITIS C
*VIRAL hepatitis
*CANCER patients
*LIVER cancer
Subjects
Details
- Language :
- English
- ISSN :
- 00302414
- Volume :
- 80
- Issue :
- 5/6
- Database :
- Academic Search Index
- Journal :
- Oncology
- Publication Type :
- Academic Journal
- Accession number :
- 65197394
- Full Text :
- https://doi.org/10.1159/000330549