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Use of 2-[[18F]]fluoro-2-deoxy- D-glucose positron emission tomography in patients with Hodgkin lymphoma in daily practice: a population-based study from Northern Italy.

Authors :
Luminari, Stefano
Cesaretti, Marina
Tomasello, Chiara
Guida, Annalisa
Bagni, Bruno
Merli, Francesco
Postiglione, Raffaella
Mangone, Lucia
Versari, Annibale
Re, Francesca
Lisi, Vincenzo De
Ruffini, Livia
Ferretti, Stefano
Cuneo, Antonio
Federico, Massimo
Source :
Leukemia & Lymphoma. Sep2011, Vol. 52 Issue 9, p1689-1696. 8p. 1 Diagram, 3 Charts, 3 Graphs.
Publication Year :
2011

Abstract

We conducted a population-based study to assess how positron emission tomography (PET) is currently used in patients with Hodgkin lymphoma (HL). Four cancer registries from northern Italy were used to identify patients with HL diagnosed from 2006 to 2008. Computed tomography (CT) and PET scans were collected before treatment start (B), at the end (F), and during treatment (I). One hundred and thirty-six patients were identified as the study population. B-PET, I-PET, and F-PET were performed in 82%%, 65%%, and 85%% of patients, respectively. Overall, I-PET was coded as positive in 16%% of cases. F-PET was positive in 13%% of cases. The I-PET result was a prognostic factor for failure-free survival (FFS) (hazard ratio [[HR]] 5.33); the F-PET result was the only prognostic factor for overall survival (OS) (HR 14.2). This population-based study confirms the prognostic role of I-PET for FFS also in daily practice; the results of F-PET can be used to predict OS. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10428194
Volume :
52
Issue :
9
Database :
Academic Search Index
Journal :
Leukemia & Lymphoma
Publication Type :
Academic Journal
Accession number :
64842650
Full Text :
https://doi.org/10.3109/10428194.2011.580475