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Immune tolerance induction with a factor VIII concentrate containing von Willebrand factor (Haemoctin SDH®) in 14 patients with severe haemophilia A.

Authors :
BIDLINGMAIER, C.
KURNIK, K.
ESCURIOLA-ETTINGSHAUSEN, C.
JAGER, R.
KLAMROTH, R.
MALE, C.
MAROSI, A.
NEMES, L.
VON STACKELBERG, A.
KREUZ, W.
Source :
Haemophilia. Sep2011, Vol. 17 Issue 5, pe837-e840. 4p. 6 Charts.
Publication Year :
2011

Abstract

The article discusses the study that evaluates the effectiveness of Immune tolerance induction with a factor VIII concentrate containing von Willebrand factor in treating patients with haemophilia A. It reveals that all patients achieved immune tolerance and successfully changed to standard prophylaxis after median 17.6 months. It found no difference concerning success rate between the two groups when the one patient who withdrew treatment is not considered.

Details

Language :
English
ISSN :
13518216
Volume :
17
Issue :
5
Database :
Academic Search Index
Journal :
Haemophilia
Publication Type :
Academic Journal
Accession number :
64838417
Full Text :
https://doi.org/10.1111/j.1365-2516.2011.02577.x