Recyclable nanoparticulate copper mediated synthesis of naphthoxazinones in PEG-400: a green approach

Authors :: Kumar, Ajeet
Saxena, Amit
Dewan, Manika
De, Arnab
Mozumdar, Subho
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Sep2011, Vol. 52 Issue 38, p4835-4839. 5p.
Publication Year :: 2011
Abstract: Abstract: An efficient methodology employing copper nanoparticles for the preparation of 2-naphthol condensed 1,3-oxazinone derivatives employing one-pot condensation reaction in the presence of K2CO3 and copper nanoparticles in PEG-400 is described which offers several advantages, viz. high yields, clean reaction, short reaction times, recyclability of the catalyst and simple workup procedure. PEG-400 was found to be the best solvent out of a range of solvents examined for this scheme. Moreover, PEG could stabilize the nanoparticles from oxidation and thus could increase the catalyst efficiency by escalating the TON (Turn over Number) and TOF (Turn over Frequency) of the catalyst, making the protocol greener, eco-friendly and environmentally benign. [Copyright &y& Elsevier]

Subjects :: *ORGANIC synthesis
*COPPER catalysts
*POLYETHYLENE glycol
*NANOPARTICLES
*CONDENSATION
*OXIDATION
*CHEMICAL reactions
*SOLVENTS
CATALYSTS recycling

Language :: English
ISSN :: 00404039
Volume :: 52
Issue :: 38
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 64481947
Full Text :: https://doi.org/10.1016/j.tetlet.2011.07.016

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