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Renal Complications in Multiple Myeloma and Related Disorders.

Renal Complications in Multiple Myeloma and Related Disorders.

Authors :
Faiman, Beth M.
Mangan, Patricia
Spong, Jacy
Tariman, Joseph D.
the International Myeloma Foundation Nurse Leadership Board
Source :
Clinical Journal of Oncology Nursing. Aug2011 Supplement, Vol. 15, p66-76. 11p. 1 Color Photograph, 4 Charts.
Publication Year :
2011

Abstract

Kidney dysfunction is a common clinical feature of symptomatic multiple myeloma. Some degree of renal insufficiency or renal failure is present at diagnosis or will occur during the course of the disease and, if not reversed, will adversely affect overall survival and quality of life. Chronic insults to the kidneys from other illnesses, treatment, or multiple myeloma itself can further damage renal function and increase the risk for additional complications, such as anemia. Patients with multiple myeloma who have light chain (Bence Jones protein) proteinuria may experience renal failure or progress to end-stage renal disease (ESRD) and require dialysis because of light chain cast nephropathy. Kidney failure in patients with presumed multiple myeloma also may result from amyloidosis, light chain deposition disease, or acute tubular necrosis caused by nephrotoxic agents; therefore, identification of patients at risk for kidney damage is essential. The International Myeloma Foundation's Nurse Leadership Board has developed practice recommendations for screening renal function, identifying positive and negative contributing risk and environmental factors, selecting appropriate therapies and supportive care measures to decrease progression to ESRD, and enacting dialysis to reduce and manage renal complications in patients with multiple myeloma. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10921095
Volume :
15
Database :
Academic Search Index
Journal :
Clinical Journal of Oncology Nursing
Publication Type :
Academic Journal
Accession number :
64133615
Full Text :
https://doi.org/10.1188/11.CJON.S1.66-76