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Synthesis of dispiro[oxindole-pyrrolidine]-thiazolo[3,2- a][1,3,5]triazines by 1,3-dipolar cycloaddition.
- Source :
-
Journal of Heterocyclic Chemistry . Jul2011, Vol. 48 Issue 4, p836-839. 4p. 2 Diagrams, 1 Chart. - Publication Year :
- 2011
-
Abstract
- The 1,3-dipolar cycloaddition of an azomethine ylide generated by a decarboxylative route from sarcosine and isatin to 7-arylmethylidene-3-aryl-3,4-dihydro-2 H-thiazolo[3,2- a][1,3,5]triazin-6(7H)-ones afforded novel dispiro[oxindole-pyrrolidine]-thiazolo[3,2- a][1,3,5]triazines in moderate yields. The structures of the products were determined and characterized thoroughly by NMR, MS, IR, and elemental analysis. The results of experiment indicated that this 1,3-dipolar cycloaddition proceeded with high stereoselectivity and regioselectivity. J. Heterocyclic Chem., (2011). [ABSTRACT FROM AUTHOR]
- Subjects :
- *ORGANIC synthesis
*TRIAZINES
*RING formation (Chemistry)
*SARALASIN
*ISATIN
Subjects
Details
- Language :
- English
- ISSN :
- 0022152X
- Volume :
- 48
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Heterocyclic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 63068978
- Full Text :
- https://doi.org/10.1002/jhet.647