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Recovery of Autonomic Nervous Activity after Myocardial Infarction Demonstrated by Short-term Measurements of SDNN.
- Source :
-
Scandinavian Cardiovascular Journal . May2001, Vol. 35 Issue 3, p186-191. 6p. 5 Charts. - Publication Year :
- 2001
-
Abstract
- Objective - Heart rate variability (HRV) has been demonstrated to be a risk factor after acute myocardial infarction (AMI). In the present study serial measurement of SDNN (standard deviation of the mean of qualified NN-interval) in short intervals was used to assess HRV changes after AMI, and determine the role of these as independent risk factors compared to clinical, arrhythmic, ischemic and anamnestic variables. Measurements from a normal healthy middle-aged male population were used as reference (n = 63). Methods - SDNN from a five-minute period during day and night-time, respectively, was examined in 103 patients 1 week (n = 54), 1 month (n = 72) and 12-16 months (n = 54) after infarction. Results - Day SDNN did not change during one-and-a-half years after AMI, and was significantly reduced compared with healthy males. Night SDNN, low after 1 week, with recovery 1 month after AMI, was significantly reduced compared with healthy males early, but not late after AMI. Thus, the study indicated during day-time a continuous abnormal sympathetic preponderance in the course of 16 months after AMI, and during night-time a gradual recovery of parasympathetic preponderance beginning early after AMI. Conclusion - One week after AMI day-time SDNN of <30 ms, and night-time SDNN of <18 ms, age ≥60 years, and myocardial ischemia (Holter monitoring) were independent predictors of 9 years' mortality. One and 12-16 months after AMI reduced day and night-time SDNN had no prognostic implication. [ABSTRACT FROM AUTHOR]
- Subjects :
- *AUTONOMIC nervous system
*MYOCARDIAL infarction
*ANGINA pectoris
Subjects
Details
- Language :
- English
- ISSN :
- 14017431
- Volume :
- 35
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Scandinavian Cardiovascular Journal
- Publication Type :
- Academic Journal
- Accession number :
- 6263231
- Full Text :
- https://doi.org/10.1080/140174301750305063