Synthesis, characterization, and biological activity of some lanthanide ternary complexes.

Five complexes have been synthesized by the reaction of lanthanide(III) nitrate with 2-thenoyltrifluoroacetone (HTTA) and p-hydroxybenzoic acid (L). The complexes have been characterized by elemental analysis, molar conductivity, FT-IR, UV-Vis, 1H NMR, TG-DTA, XPS, and transmission electron microscope. The general formula of the complexes is Na[Ln(TTA)3L] (Ln = La3+, Ce3+, Nd3+, Eu3+, Er3+). The antibacterial activities indicate that all five complexes exhibit antibacterial ability against Escherichia coli and Staphylococcus aureus with broad antimicrobial spectrums. The antitumor activity of the five complexes against K562 tumor cell in vitro is measured using methyl thiazolyl tetrazolium (MTT) colorimetry. The results show that the complexes induce K562 tumor cell apoptosis, and the complexes exhibit inhibitory effect on leukemia K562 cells. [ABSTRACT FROM AUTHOR]