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Structural Features Underlying the Multisite Phosphorylation of the A Domain of the NF-AT4....

Authors :
Marin, Oriano
Burzio, Veronica
Boschetti, Marco
Meggio, Flavio
Allende, Catherine C.
Allende, Jorge E.
Pinna, Lorenzo A.
Source :
Biochemistry. 1/15/2002, Vol. 41 Issue 2, p618. 10p. 2 Diagrams, 2 Charts, 7 Graphs.
Publication Year :
2002

Abstract

Focuses on the role of phosphorylation and dephosphorylation of NF-AT family of transcription factors in activation of T lymphocyte and control of immune response. Modification of NF-AT region by protein kinase; Importance of acidic cluster of amino acid for high-efficiency phosphorylation; Isolation of partially purified rat liver cytosol.

Details

Language :
English
ISSN :
00062960
Volume :
41
Issue :
2
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
6222061
Full Text :
https://doi.org/10.1021/bi0112309