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CD4+CD28null T lymphocytes are expanded in young women with polycystic ovary syndrome
- Source :
-
Fertility & Sterility . Jun2011, Vol. 95 Issue 8, p2651-2654. 4p. - Publication Year :
- 2011
-
Abstract
- Women affected by polycystic ovary syndrome (PCOS) have an increased risk of cardiovascular disease. We demonstrated that women with PCOS showed an expansion of CD4+CD28null T cells, an aggressive population of T lymphocytes that has been recently associated with recurrent coronary instability and type 2 diabetes mellitus. This sheds new light on possible mechanisms responsible for the higher rate of cardiovascular disease among women with PCOS. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00150282
- Volume :
- 95
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Fertility & Sterility
- Publication Type :
- Academic Journal
- Accession number :
- 61980509
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2011.01.129