Risk of Incident Diabetes With Intensive-Dose Compared With Moderate-Dose Statin Therapy: A Meta-analysis.

The article discusses a study which examined whether intensive-dose statin therapy is linked with increased risk of new-onset diabetes compared with moderate-dose statin therapy. It notes that statin therapy is known for reducing cardiovascular events such as stroke and coronary revascularization among those with and without diabetes mellitus. Results showed that a total of 2,749 individuals developed diabetes in five statin trials and 6,684 experienced cardiovascular events. For participants receiving intensive therapy, odds ratios were found to be 1.12 for new-onset diabetes and 0.84 for cardiovascular events. The study also found that there were 155 cardiovascular events needed to treat per year for intensive-dose therapy.