Effect of Epithermal Neutrons on Viability of Glioblastoma Tumor Cells in Vitro.

Authors :: Mostovich, L. A.
Gubanova, N. V.
Kutsenko, O. S.
Aleinik, V. I.
Kuznetsov, A. S.
Makarov, A. N.
Sorokin, I. N.
Taskaev, S. Yu.
Nepomnyashchikh, G. I.
Grigor'eva, E. V.
Source :: Bulletin of Experimental Biology & Medicine. Jun2011, Vol. 151 Issue 2, p264-267. 4p. 1 Black and White Photograph, 1 Chart, 2 Graphs.
Publication Year :: 2011
Abstract: We studied in vitro effect of epithermal neutrons in various doses on viability of glioblastoma U87 tumor cells. Increasing the dose from 1.9 to 4.1 Sv promoted cell death. Cytofluorimetric analysis revealed no activation of apoptosis in the irradiated cells, which attested to necrotic death of the tumor cells exposed to epithermal neutron radiation. [ABSTRACT FROM AUTHOR]

Subjects :: *GLIOBLASTOMA multiforme
*CANCER cells
*CELL proliferation
*APOPTOSIS
*BORON-neutron capture therapy
*CYTOFLUOROMETRY

Full Text Access

Tools