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Improved picture naming in aphasia patients treated with cathodal tDCS to inhibit the right Broca's homologue area.
- Source :
-
Restorative Neurology & Neuroscience . 2011, Vol. 29 Issue 3, p141-152. 12p. - Publication Year :
- 2011
-
Abstract
- Purpose: Previous reports have suggested that noninvasive cortical stimulation could influence speech production in patients with chronic stroke. Here, we evaluated the hypothesis that cathodal transcranial DC stimulation (ctDCS), a technique that decreases excitability of stimulated cortical sites, applied over a healthy right Broca's homologue area could improve picture naming in patients with post-stroke aphasia. Methods: Ten right-handed patients with post-stroke aphasia were enrolled in this double blind, counterbalanced sham-controlled, crossover study. Each patient received an intervention of ctDCS (2 mA for 20 min) and of sham tDCS (2 mA for 1 min) daily for 5 consecutive days in a randomized crossover manner with a minimum interval of one week between interventions, over a healthy right Broca's homologue area using a left supraorbital anode and simultaneous daily sessions of conventional word-retrieval training. The primary endpoint measure of this study was a standardized, validated Korean version of the Boston Naming Test, which is a measure of picture naming skills. Results: ctDCS was not found to have any adverse effects. Furthermore, significantly improved picture naming (p = 0.02) was observed at 1 hour following the last (5th) ctDCS treatment session, but no changes were observed after sham tDCS. Conclusion: These results demonstrate that cathodal tDCS over the right healthy Broca's homologue area with a left supraorbital anodal location can improve picture naming task performance in post-stroke aphasia. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09226028
- Volume :
- 29
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Restorative Neurology & Neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 60572014
- Full Text :
- https://doi.org/10.3233/rnn-2011-0587