An efficient fluoride-mediated O-arylation of sterically hindered halophenols with silylaryl triflates under mild reaction conditions

Authors :: Gebara, Karimi S.
Casagrande, Gleison A.
Raminelli, Cristiano
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2011, Vol. 52 Issue 22, p2849-2852. 4p.
Publication Year :: 2011
Abstract: Abstract: The reaction between 2,6-dihalophenols and 2-(trimethylsilyl)aryl triflates in the presence of CsF using acetonitrile as solvent at room temperature led to the formation of functionalized diaryl ethers in very good yields. [Copyright &y& Elsevier]

Subjects :: *FLUORIDES
*ARYLATION
*STERIC hindrance
*PHENOLS
*CHEMICAL reactions
*ETHERS
*ACETONITRILE
*SOLVENTS

Language :: English
ISSN :: 00404039
Volume :: 52
Issue :: 22
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 60379113
Full Text :: https://doi.org/10.1016/j.tetlet.2011.03.124

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