Dramatic inhibition of amiodarone metabolism induced by grapefruit juice.

Authors :: Libersa, Christian C.
Brique, Serge A.
Motte, Kokou B.
Caron, Jacques F.
Guédon-Moreau, Laurence M.
Humbert, Luc
Vincent, A.
Devos, Patrick
Lhermitte, Michel A.
Source :: British Journal of Clinical Pharmacology. Apr2000, Vol. 49 Issue 4, p373. 6p. 2 Graphs.
Publication Year :: 2000
Abstract: Examines the inhibition of amiodarone metabolism induced by grapefruit juice. Identification of the drug kinetics of grapefruit juice; Evaluation of the pharmacokinetics on the adult volunteers; Prescription recommendation on the antiarrhythmic drug indication.

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