The Influence of Flightless I: Regeneration versus Wound Healing.

The molecular mechanisms involved in organ regeneration has biomedical implications in regenerative medicine. In this issue, Waters et al. demonstrate that levels of the established negative wound healing factor Flightless I (Flii) modulate the hair follicle's capacity to regenerate a fiber-forming bulb after amputation. Still to be investigated are the specific pathways through which Flii influences regeneration as compared with wound healing. [ABSTRACT FROM AUTHOR]